This study focuses on Cardioprotective strategies.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
2,000
Conventional primary PCI in STEMI with implantation of DES.
Primary PCI in STEMI with implantation of DES. Following re-opening of the culprit artery mechanical postconditioning with 4 cycles of 30/30 sec. reperfusion/re-occlusion i performed.
In STEMI re-opening of the artery with guidewire/thrombectomy/small size balloon inflation DES stenting is postponed for 48 hours.
Department of Cardiology, Aalborg University Hospital
Aalborg, Denmark
Department of Cardiology, Skejby University Hospital
Aarhus, Denmark
The Heart Center, Rigshospitalet, University of Copenhagen
Copenhagen, Denmark
Department of Cardiology, Gentofte University Hospital
Hellerup, Denmark
All cause mortality, heart failure (postconditioning)
Time frame: 2 years
Infarct size in relation to area at risk as determined by MRI after 3 month
Infarct size Salvage index
Time frame: 3 month
All cause mortality, myocardial infarction, repeat revascularisation and occurrence of definite stent thrombosis according to ARC definition within 1 year (deferred stent strategy)
Time frame: 1 year
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Department of Cardiology, Odense University Hospital
Odense, Denmark