Desflurane Versus Propofol in the Sitting Position

Gachon University Gil Medical Center40 enrolled

Overview

The investigators hypothesized that both propofol and desflurane would decrease the regional oxygen saturation (rSO2) but propofol is likely to reduce rSO2 more than sevoflurane when patients are raised to the sitting position.

The investigators hypothesized that both propofol and desflurane would decrease the rSO2 but propofol is likely to reduce rSO2 more than sevoflurane when patients are raised to the sitting position. Therefore, the purpose of this study was to investigate the effect of desflurane and propofol on rSO2 values during the beach chair position for shoulder arthroscopy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Cerebral Ischemia

Interventions

propofolDRUG

anaesthesia was induced with the effect-site concentration of propofol 5.0 μg ml-1 mainly.

DesfluraneDRUG

anaesthesia was maintained by desflurane 4-7vol%

alfentanilDRUG

administration of alfentanil 10 μg kg-1 for anesthetic induction

Eligibility

Sex: ALLMin age: 20 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Forty patients, * ASA class I or II, * undergoing shoulder arthroscopy Exclusion Criteria: * Patients with history of cerebrovascular disease, coronary occlusive disease and/or obesity (body mass index \> 30) were excluded from this study.

Outcomes

Primary Outcomes

Regional Cerebral Oxygen Satuation (rSO2)

definitive values of regional cerebral oxygen saturation(rSO2,%) values are described as mean (SD)

Time frame: 1, 3, 5, 7, and 9 min after the beach chair position

Data from ClinicalTrials.gov

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