Effect of Positive End Expiratory Pressure (PEEP) on Cerebral Oxymetry During Laparoscopy

Gachon University Gil Medical Center30 enrolled

Overview

The investigators hypothesized that positive end expiratory pressure (PEEP) would increase the regional oxygen saturation (rSO2).

The investigators hypothesized that PEEP would increase the rSO2 during laparoscopic surgery by improving oxygenation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Cerebral Ischemia

Interventions

zero end-expiratory pressurePROCEDURE

positive end expiratory pressure 0 cm H2O during peumoperitoneum

positive end expiratory pressurePROCEDURE

PEEP 0 cmH2O

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA PS I or II adult patient undergoing laparoscopic low anterior resection with Trendelenburg position Exclusion Criteria: * Patients with history of cerebrovascular disease, coronary occlusive disease and/or obesity (body mass index \> 30) were excluded from this study.

Locations (1)

Gachon University Gil Hospital

Incheon, South Korea

Outcomes

Primary Outcomes

cerebral ischemia

induction 10 min, Pneumoperitoneum 20 min, after PEEP apply 40 min, time of operation ending cerebral oxymetry, cerebral perfusion pressure record

Time frame: change from baseline in rSO2 at every events

Data from ClinicalTrials.gov

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