StrataGraft® Skin Tissue as an Alternative to Autografting Deep Partial-Thickness Burns

Inclusion Criteria: * Men and women aged 18-65 years, inclusive * Written informed consent * Sufficient healthy skin identified and designated as a donor site in the event that the StrataGraft treatment site requires autografting * Complex skin defects of 3-49% TBSA requiring excision and autografting * Total burn may consist of more than one wound area * Deep partial-thickness thermal burn(s) with total area of 88 to 880 cm2 requiring excision and autografting * First excision and grafting of treatment sites Exclusion Criteria: * Pregnant women and prisoners * Patients receiving systemic immunosuppressive therapy * Patients with a known history of malignancy * Preadmission insulin-dependent diabetic patients * Patients with concurrent conditions that in the opinion of the investigator may compromise patient safety or study objectives * Expected survival of less than three months * Participation in the treatment group of an interventional study within preceding 90 days prior to enrollment * Full-thickness burns will be excluded as treatment sites * Chronic wounds will be excluded as treatment sites * The face, head, neck, hands, feet, buttocks, and areas over joints will be excluded as treatment sites * Treatment sites adjacent to unexcised eschar * Clinical suspicion of burn wound infection at the anticipated treatment sites