Safety and Efficacy Study of Renal Artery Ablation in Resistant Hypertension Patients

Inclusion Criteria: * Office systolic blood pressure that remains ≥160 mmHg (≥150 mmHg for patient with type 2 diabetes) despite the stable use of ≥3 antihypertensive medications concurrently at maximally tolerated doses, of which one is a diuretic, for a minimum of 14 days prior to enrollment * Age ≥18 and ≤80 years old * Able and willing to provide written informed consent to participate in the study * Able and willing to comply with the required follow-up schedule Exclusion Criteria: * Prior renal artery intervention (balloon angioplasty or stenting) * Evidence of renal artery atherosclerosis (defined as a stenotic severity of \>30%) in either renal artery * Multiple main renal arteries in either kidney * Main renal arteries \<4 mm in diameter or \<20 mm in length * eGFR of \<45 mL/min per 1.73 m2 using the MDRD formula * Type 1 diabetes * Renovascular hypertension or hypertension secondary to other renal disorders (glomerulonephritis, polycystic kidney disease, end-stage renal failure) * Others