Q-Trial in Patients With Hepatitis C

Inclusion Criteria: * All participants will have detectable HCV RNA in serum; stable viral load within the previous year (no fluctuation \> 2 log scale). * All participants are either treatment-naïve and unwilling to be treated with standard HCV therapies, or were not able to tolerate hepatitis C antiviral due to side effects and completed treatment more than 6 months prior to enrollment into our trial. * Age range will be from 18-65 years old * ECOG performance status \<2 (Karnofsky \>60%) * Life expectancy of greater than 12 months * Participants must have: * leukocytes \>3,000/mcL * absolute neutrophil count \>1,500/mm(3) * hemoglobin \>13 or \>12 g/dL for men/women * platelets \>125,000 K/mm(3) * total bilirubin \<1.5 g/dL * AST(SGOT)/ALT(SGPT) \<10 X institutional upper limit of normal * Albumin \>3.4g/dL * INR \<1.2 * Alpha Feto-protein \<50 ng/mL * creatinine within normal institutional limits OR * creatinine clearance \>60 mL/min/1.73 m2 for participants with creatinine levels above institutional normal. * All participants must exhibit the ability to understand and the willingness to sign a written informed consent document. Exclusion Criteria: * Participants who are currently on interferon +/- ribavirin or any other anti-viral therapies are excluded from our study. Participants who have previously been treated with hepatitis C antiviral therapy must have recovered from any adverse events due to the agent(s) administered. In addition, their last antiviral therapy must be more than six months prior to their enrollment in our study * Participants may not be receiving any other investigational agents * Participants with decompensated liver disease or cirrhosis will be excluded from this trial * History of allergic reactions attributed to compounds of similar chemical or biologic composition to Quercetin or any bioflavonoid agent * According to a monogram published by the Natural Medicines Comprehensive Database, drug interactions with Quercetin have been reported to occur with quinolone antibiotics and inhibition of p-glycoprotein or various cytochrome P450 enzymes including CYP3A4/ CYP2C8/ CYP2C9/ CYP2D6. Quercetin interactions with drugs can be categorized into (1) moderate interaction to be avoided based on healthy volunteer studies and (2) moderate interaction to be monitored closely based on in vitro studies demonstrating potential theoretical reduced elimination and increased effects. Screening will be performed prior to treatment. * Participants with concurrent illness including but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, untreated/active cardiac arrhythmia, psychiatric illness, active moderate alcohol use, or any social situation that would limit compliance with study protocol will be excluded from our study. * In addition, participants with any other known hepatitis etiologies (hepatitis B co-infection, hemochromatosis, alpha-1 antitrypsin deficiency, Wilson Disease, autoimmune hepatitis, alcohol, drug, obesity induced liver disease); or those with hepatocellular carcinoma will be excluded from this study. * Pregnant women are excluded from this study. * Human immunodeficiency virus (HIV)-positive subjects are excluded from our study. * In addition to renal and hepatic laboratory requirements listed above, renal and liver transplant recipients will be excluded from our study.