Is Cerazette Use Before Nexplanon Insertion Predictive for Bleeding Pattern?

Inclusion Criteria: * Healthy women, 18-40 years of age * regular menstrual cycle (period 23-35 days) Exclusion Criteria: * -Immediate previous use of progestin only contraception within 2 months * Known or suspected pregnancy * Acute tromboembolic disorder * Presence or history of hepatic disease, as long as the liver function values have not returned to normal * Undiagnosed vaginal bleeding * Known or suspected sex-steroid influenced malignancies (e.g. breast cancer) * Hypersensitivity to the active substances or to any of the excipients of the medicines * Pregnant or breast feeding within 6 weeks * The use of other medicinal products that might interact with contraceptive steroids and affect the efficacy of contraceptives and/or might may lead to bleeding irregularities (especially medicines that induce the liver enzyme systems such as cytochrome P450). Examples of active substances are: phenytoin, phenobarbital, primidone, bosentan, carbamatzepine, rifampicin and medicinal products or herbal preparations containing ST.John's wort and to a lesser extend oxcarbazepine, topiramate, felbamate and griseofulvin.