Lymphocytic Herpesviruses and Cerebrospinal Fluid Polymerase Chain Reaction (PCR)

PaijatHame Central Hospital60 enrolled

Overview

Enterovirus and herpes simplex viruses 1 and 2 are the main causative agents of central nervous system infections. Instead, the role of lymphocytic herpesviruses in the etiology of central nervous system (CNS) infections is not clear, even if there is the positive cerebrospinal fluid (CSF) polymerase chain reaction (PCR)-result for the virus. The aim of this study is to evaluate the presence of DNA from lymphocytic herpesviruses in the CSF obtained from the immunocompetent patients with CSF pleocytosis and from the patients with normal CSF leukocyte count.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Central Nervous System Infection

Eligibility

Sex: ALLMin age: 16 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Immunocompetent patients with clinical symptoms and signs of central nervous system infections and CSF pleocytosis (pleocytosis group) * Immunocompetent patients without suspicion of CNS infection and no CSF pleocytosis (non-pleocytosis group) Exclusion Criteria: * Suspicion of CNS-infection, eg. encephalitis, but no CSF leukocytosis (pleocytosis group) * Patients without symptoms of CNS infection, but who has CSF pleocytosis of unknown origin (non-pleocytosis group)

Locations (1)

PaijatHame Central Hospital

Lahti, Finland

Central Contacts

Laura MA Kupila

CONTACT

+358447195940 laura.kupila@phsotey.fi

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.