The purpose of the study is to find out if taking a dose of gabapentin 600 mg by mouth (po) before surgery will help prevent the development of tourniquet pain and hypertension while the tourniquet is inflated during orif of tibia fracture.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Given one hour before surgery
Placebo pill given
Ben Taub General Hospital
Houston, Texas, United States
Incidence of tourniquet-induced hypertension
Primary outcome is incidence of tourniquet-induced hypertension, which is defined as an increase of systolic or diastolic blood pressure \> 30% from baseline. This will be looked at during the time of tourniquet inflation (from inflation to deflation) during the actual surgical procedure. Usual maximum inflation time is 120 minutes.
Time frame: During the tourniquet inflation time period
Postoperative pain
Postoperative pain scores for 24 hours after surgery
Time frame: 24 hours
Narcotic use
Total use of morphine, vicodin during 24 hours after surgery
Time frame: 24 hours
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