APOL1 Gene Variants in African American Kidney Transplant Recipients

Aim 1: Inclusion Criteria: * self-reported African American * 18 years or older * kidney transplant within 12 years Aim 2: Inclusion Criteria for patients with recurrent disease: * self-reported African American * 18 years or older * kidney transplant within 12 years * recurrent or de novo glomerular disease on allograft kidney biopsy Inclusion Criteria for control group: * self-reported African American * 18 years or older * kidney transplant within 12 years * end stage kidney disease due to glomerular nephritis, clinically diagnosed or by native kidney biopsy Exclusion Criteria for control group: * clinical evidence of recurrent disease (presence of proteinuria, hematuria, Creatinine \>2) Aim 3: Inclusion Criteria: * self-reported African American * 18 years or older * scheduled living kidney transplant