Monocytes may be separated into phenotypically and functionally distinct cell types by the presence or absence of the lipopolysaccharide receptor CD14 and the Fcγ-receptor CD16. The investigators hypothesize that the total numbers of CD16+ monocytes are significantly related to cardiovascular outcome in patients with angiographically proven coronary heart disease.
Study Type
OBSERVATIONAL
Enrollment
1,000
University Clinic of the Martin Luther-University Halle-Wittenberg
Halle, Please Select, Germany
Absolute numbers of CD16+ monocytes stratified by tertiles related to the incidence of the combined endpoint
Incidence of the combined endpoint (non-fatal myocardial infarction, cardiovascular death, stroke) during a follow-up of 12 months
Time frame: 12 months
Absolute numbers of CD16+ monocytes stratified by tertiles related to the incidence of each part of the combined endpoint + total death
* non-fatal myocardial infarction * cardiovascular death * stroke * total death
Time frame: 12 months
Subgroup analysis for absolute numbers of CD16+ monocytes stratified by tertiles in relation to the combined endpoint
Subgroups of patients: Patients with stable Angina Patients with acute coronary syndrome
Time frame: 12 months
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