This observational study is designed to analyse the urinary mRNA expression of Foxp3 and Vimentin, two genes involved in tolerance and early graft dysfunction in 500 renal transplant recipients from 17 renal transplant site in France and to determine the predictive value of these gene expression on the one year graft outcome including graft function, one-year graft histological analysis and incidence of acute rejection.
This observational study is designed to analyse the urinary mRNA expression of Foxp3 and Vimentin, two genes involved in tolerance and early graft dysfunction in 500 renal transplant recipients from 17 renal transplant site in France and to determine the predictive value of these gene expression on the one year graft outcome including graft function,
Study Type
OBSERVATIONAL
Enrollment
266
urinary sample at month 3, 6 and 12
Henri Mondor Hospital
Créteil, France
Foxp3 and Vimentin mRNA expression
evaluation at month 9 suppressed by amendment n°2
Time frame: at Month 1,3,6 and 12
Renal biopsy
Time frame: at Month 12
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