HYPID study is an observational and prospective study of patients with interstitial lung disease and pre capillary hypertension diagnosed by right heart sided catheterization. The primary aim of the study is to identify prognostic factors.
Pre capillary pulmonary hypertension (PH) may be present in patients with diffuse interstitial lung disease. In this context, PH represents an important factor of morbidity and mortality for these patients. One of the purposes of HYPID is to determine predictive factors of mortality within this cohort of patients. In order to reach that aim,the study includes an evaluation based on exams conducted for the routine follow-up of patients. Each patient will be followed during 2 years at least.
Study Type
OBSERVATIONAL
Enrollment
224
Louis Pradel Hospital (Bâtiment A4)
Lyon, Bron, France
Overall survival
Determine predictive factors of mortality
Time frame: 2 years
Progression-free survival (1)
Determine cause of death
Time frame: 2 years
Progression-free survival (2)
Determine survival and time to worsening
Time frame: 2 years
Progression-free survival (3)
Analyse clinical, functional respiratory, hemodynamic features and changing characteristics of pulmonary hypertension
Time frame: 2 years
Progression-free survival (4)
Document the efficacy of PH specific treatment
Time frame: 2 years
Progression-free survival (5)
Evaluate the level of pulmonary arterial hypertension and compare the functional characteristics of patients with moderate or severe pulmonary hypertension
Time frame: 2 years
Progression-free survival (6)
Analyse clinical, functional respiratory, hemodynamic features and changing characteristics of pulmonary hypertension
Time frame: 2 years
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