This study is designed to evaluate the feasibility and diagnostic performance of a novel rapid regadenoson stress CMR protocol for detecting of obstructive coronary artery disease.
This is a single center, open-label, pilot study in subjects scheduled for invasive coronary angiography for evaluation of coronary artery disease. The primary objective is to evaluate the profile of sensitivity, specificity, and diagnostic accuracy of a novel rapid regadenoson stress CMR protocol for detection of \>= 70 coronary artery stenosis on invasive coronary angiography. Additionally the objective will be to compare the time for performance of this novel rapid regadenoson stress CMR protocol in comparison to the standard stress CMR protocol.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
50
Intravenous administration of 0.4 mg dose of Regadenoson using per routine CMR, as indicated in the package insert.
The Methodist Hospital
Houston, Texas, United States
RECRUITINGProfile of sensitivity, specificity, and diagnostic accuracy of rapid regadenoson stress CMR.
Evaluate the profile of sensitivity, specificity, and diagnostic accuracy of a rapid regadenoson stress CMR protocol for the detection of \>= 70% stenosis of a major epicardial coronary artery on invasive coronary angiography.
Time frame: Up to 7 days
Evaluate time for performance of rapid regadenoson stress CMR protocol.
Evaluate duration of time for performance of rapid regadenoson stress CMR protocol in comparison to time for performance of standard regadenoson stress CMR protocol.
Time frame: Up to 7 days
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