Cardiac surgery including hypothermic cardiac arrest (HCA) commonly involves perioperative transfusion of allogeneic blood products which is associated with increased morbidity and mortality. In this retrospective analysis, the investigator aimed to evaluate the effect of a thromboelastometry-guided treatment algorithm promoting fibrinogen concentrate as first line hemostatic agent on the perioperative use of allogeneic blood products.
The investigators will analyze the data of patients undergoing elective and emergent surgical procedures involving the ascendent aorta and/or the aortic arch with the help of HCA from January 2009 to June 2011. The investigators will collect and document baseline characteristics, the use of thromboelastometry, thromboelastometric data, and perioperative laboratory data. In addition, the investigators will evaluate perioperative bleeding from mediastinal drainages, perioperative use of blood and hemostatic products, and the adverse events within the hospitalisation including re-exploration, renal impairment, myocardial infarction, severe brain injury, and death.
Study Type
OBSERVATIONAL
Enrollment
200
University Hospital Basel, Department of Anesthesia and Intensive Care Medicine
Basel, Canton of Basel-City, Switzerland
Transfusion of allogeneic blood products
Time frame: within 24 hours including surgery
Proportion of patients without allogeneic blood products
Time frame: 24 hours including surgery
Adverse events
Adverse events include: renal impairment (RIFLE criteria), stroke, severe neurologic impairment, myocardial infarction, death, re-exploration
Time frame: within 24 hours including surgery
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.