Evaluation of PillCam With Blood-Sensing Feature: A Feasibility Study

Inclusion Criteria: Group A (Healthy subjects) * Subject's age is 18 to 45 years old * Subject is an healthy volunteer * Subject agrees to sign the Informed Consent Form Group B (Symptomatic Patients) * Age ≥ 18 years * The subject was referred to Gastroscopy for at least one of the following reasons: 1. History of acute, overt UGI hemorrhage, defined as hematemesis (fresh blood or coffee grounds) and/or melena within the 48 hours prior to patient presentation 2. Subject has ongoing overt gastrointestinal bleeding with hematochezia or melena 3. Subject has Iron Deficiency Anemia ,FOBT(+) and negative colonoscopy examination 4. Other known or suspected cause of acute upper GI bleeding * Subject agrees to sign the Informed Consent Form Exclusion Criteria: 1. Subject has Dysphagia, odynophagia, known swallowing disorder or history of Zencker's diverticulum 2. Subject is known or is suspected to suffer from bowel obstruction or bowel perforation at the time of presentation 3. Subject has history of prior bowel obstruction 4. Subject suffers UGI hemorrhage with hemodynamic shock requiring urgent endoscopy 5. Subject with any condition believed to have an increased risk for capsule retention such as Crohn's disease, intestinal tumors, radiation enteritis, incomplete colonoscopies due to obstructions or NSAID enteropathy 6. Subject has history of UGI tract surgery (e.g., Billroth I, Billroth II, esophagectomy, gastrectomy, bariatric procedure) 7. Pregnancy or nursing mothers 8. Subject has known allergy to conscious sedation medications 9. Presence of an electro-medical device (pacemaker or internal cardiac defibrillator) 10. Subject has altered mental status (e.g., hepatic encephalopathy) that would limit patient ability in swallowing the capsule 11. Known allergy to erythromycin 12. Subject is currently or within previous 30 days participating in another clinical study that may directly or indirectly affect the results of this study 13. Subject is not able to provide written informed consent.