This study is to define the optimal method of prophylaxis for patients with gastrectomy in Korea and the investigators hypothesized only mechanical method would be enough for preventing VTE on perioperative period.
Venous thromboembolism (VTE) is common and often fatal complication in patients with cancer. Gastric cancer is the most frequent cancer in Korea. The incidence of VTE would be increased in patients with gastric cancer, especially associated surgery. However, the incidence and optimal prophylactic method associated with cancer surgery are not well studied in Asian patients. Most Korean surgeon concerns regarding the increased postoperative bleeding associated with low molecular weight heparin(LMWH)prophylaxis. The incidence and adverse event will be examined to define the optimal prophylactic method of VTE in surgical patients with gastric cancer.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
682
40mg 12 hours before surgery and 12 hours later surgery
Seoul St. Mary's Hospital
Seoul, South Korea
incidence of VTE
The incidence of VTE between mechanical method only group and mechnical plus LMWH group.
Time frame: up to 30 days after operation
Adverse event
The adverse event such as bleeding will also be compared.
Time frame: up to 30 days after operation
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