MRI Results in Dupuytren's Contracture Before and After Injection With Xiaflex

Inclusion Criteria: * Subject has a diagnosis of Dupuytren's Disease affecting only the metacarpophalangeal joint of the 4th or 5th finger. * Subject has only one finger affected by the disease. * Patients will be 35 years of age of older. * Patients will be able to read, speak, and understand English or have available adequate translation assistance and be able to provide voluntary written consent to participate. Exclusion Criteria: * Female patients who are nursing or pregnant, or plan to become pregnant during the treatment phase. * Patient has a chronic muscular, neurological or neuromuscular disorder that affects the hands. * Patient has known allergy to collagenase or any other excipient of Xiaflex. * Patient has received any collagenase treatments before the first dose of Xiaflex. * Patient with abnormal coagulation, including patients who have received anticoagulant medications other than low-dose aspirin within 7 days of the injection.