This is a single center,prospective,no-controlled clinical trial
1. The complete remission of enough steroids as inducement therapy in adult minimal change disease-like IgA nephropathy patients 2. The safety of enough steroids as inducement therapy in adult minimal change disease-like IgA nephropathy patients
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
30
daily single dose of 1mg/kg (maximum 80mg) or alternate day single dose of 2mg/kg (maximum 120mg),maintained for a minimum period of 6 weeks and maximum period of 12 weeks. After achieving complete remission., corticosteroids should be tapered slowly, 10mg every two weeks tapered to reach 0.15mg/kg/d, then 2.5mg every two to four weeks tapered to reach the minimum dosage 10mg/ alternate day
Research Institute of Nephrology, Jinling Hospital, Nanjing University School of Medicine
Nanjing, Jiangsu, China
24h urinary protein excretion
Time frame: 3 months
remission rate
Time frame: 3 months
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