Dehydroepiandrosterone (DHEA) + Acolbifene Against Vasomotor Symptoms (Hot Flushes) in Postmenopausal Women

Main Inclusion Criteria: * Postmenopausal women (non-hysterectomized or hysterectomized). * Women between 40 and 75 years of age. * Willing to participate in the study and sign an informed consent. * Women having many moderate to severe hot flushes. * For non-hysterectomized women, willing to have an endometrial biopsy at baseline and end of-study. Main Exclusion Criteria: * Undiagnosed abnormal genital bleeding. * Hypertension equal to or above 140/90 mm Hg. * The administration of any investigational drug within 30 days of screening visit. * Endometrial hyperplasia (simple or complex hyperplasia with or without atypia), cancer or endometrial histology showing proliferative, secretory or menstrual type characteristics at histologic evaluation of endometrial biopsy performed at screening.