The objective of this study is to compare a standard coronary CT angiography scan protocol with conventional image reconstruction with a scan protocol using reduced tube current and a new image reconstruction algorithm. The investigators hypothesize that the image quality of the new scan protocol is not inferior, while radiation dose estimates are reduced by around 30%. Secondary endpoints of the study include quantitative image quality parameters, prevalence of non-diagnostic studies, prevalence of coronary artery plaques and plaque characteristics (calcified, non-calcified, mixed) and prevalence of follow-up examinations.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Enrollment
400
Conventional coronary CT angiography using standard reconstruction technique (filtered back projection).
Using the new scan protocol with 30 % less tube current and iterative image reconstruction algorithm.
Deutsches Herzzentrum Muenchen
Munich, Bavaria, Germany
RECRUITINGImage quality
Compared with a conventional scan protocol the use of a new scan protocol using iterative image reconstruction and reduced tube current is associated with a comparable diagnostic image quality, while the radiation dose estimates are significantly reduced.
Time frame: 1 month
Quantitative image quality parameters
Quantitative image quality parameters, e.g. image noise, signal and contrast intensity, signal- and contrast-to-noise-ratios
Time frame: 1 month
Prevalence of non-diagnostic examinations
Prevalence of non-diagnostic examinations in both study arms.
Time frame: 1 month
Prevalence of coronary artery plaques
Prevalence of coronary artery plaques and coronary artery plaques characteristics (non-calcified, calcified, mixed) in both study arms.
Time frame: 1 month
Prevalence of follow-up examinations
Prevalence of follow-up examinations in both study arms.
Time frame: 1 month
Radiation dose
Radiation dose in both study arms.
Time frame: 1 month
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