The purpose of the study is to compare an acellular epithelial skin substitute with autologous split-thickness skin grafts (STSGs) in deep partial-thickness burns. The objective is to evaluate skin quality and scar formation by using subjective and objective burn scar assessments in order to present valuable data for another additional option of wound coverage in deep partial-thickness burns. The investigators hypothesized that the acellular epithelial skin substitute is at least not inferior to autologous skin grafts.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
18
Burn wounds are covered by an acellular skin substitute and remains 10-14 days that peals away in line with re-epithelialisation
Matched burn wound is covered by autologous skin after tangential excision.
Medical University of Vienna, Burn Center, Department of Plastic and Reconstructive Surgery
Vienna, Vienna, Austria
Time (in days +/- standarddeviation) to complete re-epithelialisation in acellular skin substitue area versus autologous skin
Time to complete re-epithelialisation measured in days after surgery
Time frame: 1 year
Skin quality- ratio acellular skin substitute/healthy skin versus ratio autologous skin/healthy skin
Quality of the skin is measured two-fold: 1. Subjective scar scors: Vancouver Scar Scale, Patient and Observer Scar Scale 2. Objective scar evaluation by a non-invasive suction device, that measures viscoelastic parameter.
Time frame: 1 year
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.