The purpose of this study was to determine the most suitable effect-site concentration of remifentanil for the LMA insertion during inhaled induction with 8% sevoflurane in adults.
For practical purposes, opioids with the ability to suppress upper airway reflexes have been used to facilitate insertion of the LMA during anaesthesia induction. To date, however, there have been no published reports addressing the use of remifentanil to facilitate LMA insertion during sevoflurane inhalation induction in adults. Therefore, the purpose of this study was to determine the most suitable effect-site concentration of remifentanil target-controlled infusion (TCI) for the LMA insertion during inhaled induction with 8% sevoflurane in adults.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
102
"Remifentanil 1": "The R1 group, which received a target effect-site remifentanil concentration of 1 ng/ml.
The control group, which received an infusion of normal saline
"Remifentanil 2": "The R2group, which received a target effect-site remifentanil concentration of 2 ng/ml.
Ajou University School of Medicine
Suwon, South Korea
LMA Insertion Condition
The pre-determined effect-site concentration of remifentanil or normal saline was administered according to the patient's group.LMAs were size #3 for women and #4 for men.The conditions of the LMA insertion were graded on a three point scale using six variables (mouth opening, ease of LMA insertion, swallowing, coughing and gagging, head and body movements, laryngospasm). Each of these variables was rated as excellent, intermediate or poor.
Time frame: at that time on LMA insertion only
Frequency of Apnea
If prolonged apnoea (\> 30 s) developed, manual ventilation was assisted. And record the frequency of apnea on each group
Time frame: baseline, 30sec after drug injection
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