Gastric Cancer Metastasized to the Central Nervous System (CNS)

University of Zurich150 enrolled

Overview

Descriptive registry to investigate frequency of HER-2 positive gastric cancer involving CNS. Exploration of additional prognostic factors for brain involvement from gastric cancer.

HER2 Status E-Cadherin Status

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Gastric Cancer

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion criteria: * in order to be eligible for the study, the diagnosis of gastric cancer and/or lower esophageal cancer must be confirmed histologically. CNS involvement must be confirmed either via independent neuroradiological and/or positive CSF cytology. Exclusion criteria: * Patients whose diagnosis is not confirmed upon pathological review or where the CNS involvement cannot be confirmed after neuroradiological review will be excluded from this study.

Locations (1)

Dept Oncology, University Hospital Zürich

Zurich, Switzerland

Outcomes

Primary Outcomes

HER2 Status

Determination of HER2 Status on Tumor Tissue

Time frame: 2 years

Secondary Outcomes

Outcome according to HER2 Status

Time frame: 2 years

Data from ClinicalTrials.gov

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