Effectiveness Study of the Ivivi SofPulse for Pain Amelioration in Adults With Mild to Moderate Knee Osteoarthritis

Inclusion Criteria: * Age 40 to 80 years * Bilateral weight-bearing anteroposterior x-ray of each knee taken within the last 12 months and radiographs submitted to the Principal Investigator for evaluation * Radiographic evidence of mild to moderate (Kellgren/Lawrence grade 2 or 3) OA in at least one knee based on a weight-bearing anteroposterior x-ray taken within the last 12 months * Self-reported persistent knee pain severity of 4.0 to 8.0 cm on a 10 cm VAS for most days in the previous 2 months in at least one knee, with grade 2 or 3 OA * Able to read and complete English-language surveys * Daily access to the internet * Ability of the participant to comprehend the full nature and purpose of the study including possible risks and side effects * Consent to the study and willing to comply with study methods Exclusion Criteria: * Subjects who have any implanted metallic leads, wires, or systems (e.g. pacemaker, implantable cardioverterdefibrillator) * Self-reported persistent knee pain severity \> 8.0 cm on a 10 cm VAS in either knee for most days in the previous 2 months * Radiographic evidence of severe (Kellgren/Lawrence grade 4) OA in either knee based on a weight-bearing anteroposterior x-ray taken within the last 12 months * Self-reported diagnosis of autoimmune or inflammatory arthritis (e.g. Rheumatoid Arthritis, Lupus, etc.) * More than 8 days of narcotic pain medication in the last 30 days * Joint surgery, tidal lavage, or arthroscopy of either knee in the past 6 months * Intra-articular corticosteroid or hyaluronic acid injections of either knee in the past 6 months * Oral prednisone use in the past 30 days * Participation in any clinical trial in the past 30 days * Knee OA associated with worker's compensation or accident litigation * Regular use of a walker or wheelchair * Vulnerable populations including prisoners and nursing home residents * Anticipated move away from immediate area in next 6 months * Any medical condition that, in the opinion of the investigator, may compromise patient safety or confound the assessment of treatment effectiveness After 1-week Run-in Period * Daily average of "current" knee pain severity \< 4.0 cm, assessed on a 10 cm VAS, during the 1-week run-in period in both knees * Daily average of "current" knee pain severity \> 8.0 cm, assessed on a 10 cm VAS, during the 1-week run-in period in either knee * Daily average of "current" knee pain severity of 4.0 to 8.0 cm, assessed on a 10 cm VAS, during the 1-week run-in period in any knee with Kellgren/Lawrence grades of 0 or 1 in the same knees * Narcotic use of more than 2 days during the 1-week runin period * Noncompliance with online symptom reporting requirements