The purpose of this study is to determine the clinical impact of cerebral and systemic desaturation during liver transplantation and resection on post-operative complications.
This is an observational study. Cerebral and systemic oxymetry (rSO2) using near infrared spectroscopy (NIRS, Invos 5100; Somanet- ics Corporation, Troy, MI) will be performed on all patients with 4 optodes (right and left temporal area, arm and leg). Continuous rSO2 values will be stored on a hard disk with a 15 seconds update within intraoperative period and first 4 hours after the surgery. Desaturation phases (saturation decrease more than 20% of the basal value for more than 15 seconds) will be correlated to operative procedure or events. Postoperative adverse events will be collected. A correlation between desaturation and postoperative adverse events will be done with a multiple linear regression model.
Study Type
OBSERVATIONAL
Enrollment
100
oxymetry measurement using near infrared spectroscopy
Centre hospitalier de l'Université de Montréal (CHUM)
Montreal, Quebec, Canada
define the correlation coefficient between the number of systemic and/or cerebral desaturation phases and the number of postoperative adverse events
Time frame: from the beginning of anesthesia till 4 hours after the end of the surgery
define the prevalence of systemic and cerebral desaturation phases during hepatic surgery or transplantation
Time frame: from the beginning of anesthesia till 4 hours after the end of the surgery
define the correlation coefficient between systemic and/or cerebral desaturation phases and the length of stay in intensive care unit
Time frame: duration of intensive care stay, an expected average of 4 days
validate the equivalence of the systemic and cerebral oxymetry
Time frame: from the beginning of anesthesia till 4 hours after the end of the surgery
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