The postoperative period following cesarean is associated with moderate to severe pain that requires a considerable amount of analgesics that carry with them side-effects such as nausea, vomiting, fatigue and immobilization. Several studies have tried, with variable results, to find a more effective analgesia alternative such as infusion of local anesthetics through a catheter in the surgical wound sinus, a practice that has currently been widely used in clinical practice. Despite existing references on its use in the postoperative period following cesareans there continues to be a lack of information on other aspects. The investigators study hypothesis is that the use of levobupivacaine in the surgical wound will reduce the surface of hyperalgesia compared to the control group.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
70
continuous levobupivacaine subfascial infusion
continuous NaCl subfascial infusion
Teresa Herrera Hospital; A Coruña University Hospital Complex
A Coruña, A Coruña, Spain
Area of incisional secondary hyperalgesia
Time frame: 72 hours
Pain relief
Time frame: 72 hours
consumption of morphine (mg) and paracetamol (gr)
Time frame: 48 hours
Incidence of chronic pain
Time frame: 6 month
Pharmacokinetic variables of levobupivacaine
Cmax, Area Under Curve, Tmax
Time frame: 72 hours
Incidence of complications and/or side effects related to the technique
Time frame: 72 hours
Rate of satisfaction experienced by the patients through a survey
Time frame: 72 hours
endocrin-metabolic response
Time frame: 72 hours
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