BIPAP Vision Versus OPTIFLOW System Comparison in Acute Respiratory Failure After Cardio Thoracic Surgery

Centre Chirurgical Marie Lannelongue830 enrolled

Overview

The OPTIFLOW ™ use is becoming more common in acute respiratory failure cases, but its place in relation to VNI (Bi-PAP mode) is not yet defined. OPTIFLOW ™ vs the VNI comparison of the use, in the immediate postoperative period, should lead to define the role of each technique and lead to a optimal rationalization of patients management with acute respiratory failure after surgery.

Main objective: to determine, if the initiation of OPTIFLOW™ system immediate after cardio/ thoracic surgery with acute respiratory failure or immediate after post extubation in patients at risk, is not less than the start a VNI per BIPAP Vision ®system. In terms of reintubation rates, refusal to continue the technique, or switch to another technique proposed. Secondary objectives: * To assess changes in the sensation of dyspnea * To analyze the skin tolerance and the comfort in this population * To analyze the evolution of hemodynamic and respiratory parameters * To compare the number of bronchoscopy performed during the patient's stay in intensive care unit * Assess the number of postoperative pneumonia and antibiotic consumption * To determine whether the initiation of any treatment changes in the immediate postoperative length of stay in intensive care and comprehensive.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

830

Conditions

Respiratory Insufficiency

Interventions

Non invasive ventilation (VNI)DEVICE

BIPAP® vision

Non invasive ventilationDEVICE

OPTIFLOW system

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients after cardiac/thoracic surgery with acute respiratory failure defined by the presence of the following criteria: * report PaO2/FiO2 \<300 * Respiratory rate\> 25 for at least 2 hours * Getting involved accessory respiratory muscles * paradoxical breathing Or * In immediate after extubation, the patient will be eligible if present in the withdrawal test: * SaO2 \<90% in 12 L of O2 during a trial of spontaneous ventilation tube on * PaO2 \<10 kPa at a FiO2 ≥ 50% during a VS trial + pressure support * The presence of a risk factor: Obesity (BMI\> 30), FEVG \<40%, Failed extubation prior, stridor Exclusion Criteria: * Previous history of SAS * Patient tracheotomy * Comas non hypercapnic * bradypnea * Cardiac arrest * Gastric Surgery recent * Restlessness, lack of cooperation * Nausea, vomiting * Hemodynamic instability

Locations (1)

Centre Chirurgical MarieLannelongue

Le Plessis-Robinson, Île-de-France Region, France

Outcomes

Primary Outcomes

Failure of the ventilation system

Failure defined by reintubation rate, refusal to continue the technique, or switch to an another technique proposed breakdown

Time frame: One week

Secondary Outcomes

Sensation of dyspnea

Time frame: one week

Skin tolerance and comfort

Time frame: One week

Evolution of hemodynamic and respiratory parameters

Time frame: one week

number of bronchoscopy performed during the patient's stay in Intensive Care Unit

Time frame: one week

number of postoperative pneumonia and antibiotic use

Time frame: one week

length of stay in intensive care

Time frame: one week

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.