Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic Constipation

Phase 4CompletedNCT01460225

Dartmouth-Hitchcock Medical Center19 enrolled

Overview

This prospective study is designed to evaluate how lubiprostone may affect gastric motor and sensory function.

Study Type

INTERVENTIONAL

Allocation

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Enrollment

Conditions

Chronic Idiopathic Constipation

Interventions

lubiprostoneDRUG

24 micrograms twice daily for 1 week

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * chronic idiopathic constipation Exclusion Criteria: * medications that slow gastrointestinal (GI) motility * prior surgery to the GI tract

Locations (1)

Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, United States

Outcomes

Primary Outcomes

Gastric Emptying

gastric emptying was measured before and after 7 days of treatment.at set times (2 and 4 hours post eating a radio-labeled meal)

Time frame: Day 1 and Day 7

Data from ClinicalTrials.gov

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