Attenuated plaque ≥ 5mm by intravascular ultrasound(IVUS) was reported to be high risk for distal embolism in Acute coronary syndrome(ACS). The purpose of this study is to assess the effect of thrombus aspiration catheter and distal protection device (filter wire; Filtrap™) in the aforementioned subgroup of patients at high risk for distal embolism.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
200
Combination of distal protection device (Filtrap™ )and thrombus aspiration catheter
Thrombus aspiration catheter only
Yokohama City University Medical Center
Yokohama, Kanagawa, Japan
Incidence of no-reflow/slow-flow phenomenon after percutaneous coronary intervention (PCI)
Time frame: a day
Rise in CK-MB and troponin I or T the next morning after PCI (Peak of CK too in case of ST-segment elevation myocardial infarction )
Time frame: a day
Incidence of clinical events including mortality, major adverse cardiac events, and Hospitalization for heart failure
Time frame: 10months
Improvement of Thrombolysis in Myocardial Infarction (TIMI) flow grade compared with baseline
Time frame: 8-12months
TIMI flow grade
Time frame: 8-12months
Corrected TIMI frame count
Time frame: 8-12months
Myocardial blush grade
Time frame: 8-12months
Incidence of any revascularization
Time frame: 8-12months
Incidence of stent thrombosis
Time frame: 8-12months
Plaque protrusion by IVUS inside the stent
Time frame: 8-12months
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