Effect of Nefopam on Acute Postoperative Pain in Patients Undergoing Orthognathic Surgery

The Catholic University of Korea40 enrolled

Overview

The aim of this study is to determine the analgesic effect of perioperative nefopam on acute pain in patient undergoing orthognathic surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Pain Orthognathic Surgery

Interventions

nefopamDRUG

nefopam infusion for postoperative 24 hours

normal saline (control)DRUG

normal saline infusion for postoperative 24 hours

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * aged 20-60 years * undergoing elective orthognathic surgery Exclusion Criteria: * pregnancy * psychiatric disease * hepatobiliary or renal disease * monoamine oxidase inhibitor-taking patients

Locations (1)

Seoul St.Mary's Hospital

Seoul, Seocho-gu, South Korea

Outcomes

Primary Outcomes

pain score on the visual analogue scale

Time frame: after orthognathic surgery (up to postoperative 24 hours)

Data from ClinicalTrials.gov

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