The purpose of this study is to assess the effects of oral TR-701 free acid (FA) versus placebo on QTcF.
To assess the effects of a single therapeutic (200 mg) and supratherapeutic of oral TR-701 free acid (FA) versus placebo on QT interval corrected for heart rate using Fridericia's formula (QTcF) in healthy subjects.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
48
6 tablet of T-701 FA
1 tablet 400 mg Moxifloxacin
1 tablet of TR-701 FA with 5 tablet placebo
Trius Investigator
Dallas, Texas, United States
QTcF Change from Baseline
Time-matched, placebo adjusted change from the baseline QTcF (ΔΔQTcF).
Time frame: 24 Hours
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6 placebo tablets