Efficacy Study of Chemotherapy to Treat Advanced or Recurrent Endometrial Cancer

Inclusion Criteria: * Histologically confirmed chemotherapy naïve endometrial cancer * One of following histology Endometrioid, UPSC, CCCa, squamous, adenosquamous, mixed * FIGO stage IVb or recurrent endometrial cancer (incurable by surgery and/or RT) * At least one measurable lesion by RECIST on CT * ECOG PS: 0-2 * Age: 20-75 * Adequate organ function BM: ANC≥1,000/mm3, Plt≥100X103/mm3 Kidney: Creatinine\<1.25 × UNL이고, GFR ≥ 60 Liver: AST, ALT\< 3×UNL, T- bil\<1.5 mg/ mm3 * Informed Consent * Contraception during study period Exclusion Criteria: * Previous chemotherapy * RT, hormone therapy, or immunotherapy within 1 month * Other malignant disease * Uncontrolled medical disease * Infection requiring antibiotics * Symptomatic CHF, RF, Angina, Arrhythmia, etc. * Neurosis or psychosis * Pregnancy, breast-feeding * Etc.