Accuracy of Amniotic Fluid Lamellar Body Counting for Evaluating of Fetal Lung Maturity

Isfahan University of Medical Sciences128 enrolled

Overview

The purpose of this study is to determine the accuracy of Amniotic fluid Lamellar Body Counting for Evaluating of Fetal Lung Maturity.

Respiratory distress syndrome (RDS) is one of important cause of mortality in neonates. This study was designed to evaluate the amniotic fluid lamellar body counting for predicting fetal lung maturity.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

128

Conditions

Retained Fetal Lung Fluid

Interventions

Amniotic fluid Lamellar Body CountingOTHER

fluid samples were obtained by amniocentesis during normal delivery or before rupturing the membrane in cesarean. The samples were sent to the lab as soon as possible and after centrifuging with 500 round per minute for 3 minutes, they were placed in the cell counter machine (STKR coulter).

Eligibility

Sex: FEMALEHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Women, with 28-37 weeks of gestational age, who had been decided to terminate their pregnancy, were enrolled in the study Exclusion Criteria: * Chorioamnionitis * Intra Uterine Fetal Death (IUFD) * Blood in amniotic fluid * Rupture of placenta and patient dissatisfaction were the exclusion criteria.

Locations (1)

Al-zahra university hospital

Isfahan, Isfahan, Iran

Outcomes

Primary Outcomes

The statues of respiratory of neonates

Diagnosing of immaturity is based on the following criteria: 1-Physical examinations such as: nasal flaring, retraction, grunting, and tachypnea. 2-Oxygen needing more than 24 hours with three chest x-ray findings.

Time frame: at 2 minutes after delivery

Data from ClinicalTrials.gov

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