This is a comparison between Hypertonic versus isotonic solution in a double blind randomized trial for off pump Coronary Artery Bypass Graft (CABG) surgery targeting the left marginal branch. Hypertonic solution should provide better tolerance for heart mobilization with less volume expansion and less drugs.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
20
Use of Hypertonic solution 4 ml/Kg during left marginal branch CABG surgery.
Use of Isotonic solution 4 ml/Kg during left marginal branch CABG surgery.
Hospital Pitangueiras
Jundiaí, São Paulo, Brazil
RECRUITINGUse of vasoactive drugs in left marginal branch off pump CABG surgery
Comparison between hypertonic and isotonic solutions for need of vasoactive drugs with heart mobilization during left marginal branch off pump CABG surgery. Data will be collected respectively at 1, 5 and 10 minutes after beggining the left branch coronary anastomosis. Data will be type of drug need and dosage until the end os the anastomosis.
Time frame: time related to left branch coronary anastomosis for drug need.
Fluid balance
Comparison of fluid balance in the operative period between hypertonic and isotonic solutions. Data will be collected at the end of surgery and by next mornning.
Time frame: Operative period and first operative day
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.