LIFSCREEN : Evaluation of Whole Body MRI for Early Detection of Cancers in Subjects With P53 Mutation (Li-Fraumeni Syndrome)

Gustave Roussy, Cancer Campus, Grand Paris107 enrolled

Overview

The purpose of this study is to compare the diagnostic efficacy of two follow-up schedules for the early detection of cancers in the population under study on cancer incidence at 3 years.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

107

Conditions

Li Fraumeni Syndrome

Interventions

whole body MRIOTHER

whole body MRI at inclusion, one and two years

Eligibility

Sex: ALLMin age: 5 YearsMax age: 71 Years

Medical Language ↔ Plain English

Inclusion Criteria: * P53 mutation

Locations (1)

Institut Gustave Roussy

Villejuif, France

Outcomes

Primary Outcomes

cancer incidence

cancer incidence during the first 3 years

Time frame: 3 years

Data from ClinicalTrials.gov

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