Placebo and Active Controlled, Double Dummy Study to Compare Efficacy of Aspirin and Ibuprofen in Treatment of Episodic Tension-type Headache

Inclusion Criteria: * Ambulatory male or female, 18 to 65 years of age * Normal blood pressure * Patients suffering from episodic tension-type headache * Headache lasting from 30 minutes to 7 days * Headache had at least two of the following characteristics: Bilateral location. Pressing/tightening (non-pulsating). Mild or moderate intensity. Not aggravated by routine physical activity such as walking or climbing stairs. \- Both of the following: No nausea or vomiting. No more than one of photophobia or phonophobia. Exclusion Criteria: * Other headaches, including migraine, that required medical treatment * Hypersensitivity to acetylsalicylic acid, salicylates, ibuprofen or other non-steroidal anti-inflammatory drugs (NSAIDs) * Serious physical illness especially uncontrolled disorders of kidney, liver, lung, heart or brain function, neurological disorders or severe chronic or terminal disease * Mental illness, including depression * Needed or were using or likely to need or use any of the prohibited concomitant medications: antidepressants, oxicams * Pregnant or lactating women, or sexually active women of child-bearing potential unless using effective contraception * Participating in any other clinical study or had done within the previous 4 weeks * Had been previously enrolled in this study