The purpose of this study is to determine the efficacy and safety of 1000 mg Aspirin (study medication) by comparing 1000 mg Paracetamol (study medication) in treating the symptoms of sore throat associated with a common cold. The study is designed to develop a treatment method against sore throat associated with a common cold which will have more advantages for patients than the methods that are currently available.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
508
Single Administration of 2 tablets Acetylsalicylic acid (500 mg each); in addition, 2 tablets matching placebo to Paracetamol
Single Administration of 2 tablets Paracetamol (500 mg each); in addition, 2 tablets matching placebo to Acetylsalicylic Acid
Single Administration of 2 tablets matching Placebo to Acetylsalicylic Acid together with 2 tablets matching placebo to Paracetamol
Unnamed facility
Reading, Berkshire, United Kingdom
Unnamed facility
Manchester, Greater Manchester, United Kingdom
Unnamed facility
Chorley, Lancashire, United Kingdom
Unnamed facility
Wigan, Lancashire, United Kingdom
Unnamed facility
Liverpool, Merseyside, United Kingdom
Unnamed facility
Liverpool, Merseyside, United Kingdom
Unnamed facility
Cardiff, South Glamorgan, United Kingdom
Unnamed facility
Birmingham, West Midlands, United Kingdom
Pain intensity difference to baseline of Acetylsalicylic Acid in comparison to Paracetamol
Time frame: For 6 hours after drug intake
Pain intensity difference to baseline of Acetylsalicylic Acid in comparison to Placebo
Time frame: For 6 hours after drug intake
Total pain relief of Acetylsalicylic Acid in comparison to Paracetamol
Time frame: For 6 hours after drug intake
Total pain relief of Acetylsalicylic Acid in comparison to Placebo
Time frame: For 6 hours after drug intake
Evaluation of Upper Respiratory Tract Infection symtoms
Time frame: 2 hours after drug intake
Adverse Event collection
Time frame: Up to 17 days after Screening
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