Immediately following tooth removal, a healing process begins that affects the eventual alveolar bone volume and architecture of the alveolar ridge. Satisfactory and timely healing are essential to obtain ideal functional reconstruction. Traumatic removal of a tooth, or a poor healing response, may lead to excessive bone loss delaying tooth replacement, requiring expensive and time-consuming reconstructive surgeries, or even the inability to be corrected. The Plasma Rich in Growth Factors (PRGF-Endoret) has shown its therapeutic potential effect to minimize the consequences of this aggression, promoting the regeneration of both hard and soft involved tissues.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Enrollment
60
Clínica Dental Eduardo Anitua
Vitoria-Gasteiz, Spain
Percentage of regenerated post-extraction sockets
Time frame: 10-12 weeks
Regenerated bone volume
Measurement of the regenerated bone volume at final follow-up in relation to the initial post-extraction socket total volume measured by CT-Scanner and expressed as a percentage.
Time frame: 10-12 weeks
Post-operative pain (VAS)
Time frame: 3, 7 and 15 days post-extraction
Soft Tissue Healing Index
Time frame: 3, 7 and 15 days post-extraction
Inflammation
Using a specific 0 to 3 Inflammation Score
Time frame: 3, 7 and 15 days post-extraction
Adverse events or complications
Time frame: 10-12 weeks
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