The Effect of Oxytocin on Fear Memory Consolidation Novel Intervention to Prevent Posttraumatic Stress Disorder (PTSD)

Inclusion Criteria: * Men or women 18 to 65 years of age * Score in study range on the Neuroticism-Extraversion-Openness-Five Factor Inventory (NEO-FFI) * No current Axis I Diagnostic and Statistical Manual-IV (DSM) excluded diagnoses as determined by the Structured Clinical Interview DSM (SCID) completed within the past 4 months. * Must be able and willing to understand study procedures and return to the clinic on two separate consecutive days for the fear-conditioning procedures. * Subjects must be able to give informed consent and be willing and able to comply with study procedures. Exclusion Criteria: * Presence of a current DSM-IV Axis I diagnosis as measured by the SCID. * A serious medical condition or other condition deemed likely to result in surgery or hospitalization, or which would make participation in the study difficult. * Patients with a history of trauma resulting in head injury related seizures or with epilepsy (except a prior history of febrile seizures of infancy which are not exclusionary). * Use of supplemental hormones (birth control, estrogen, testosterone, prednisone, etc) or narcotics. * Pregnant or lactating women. * Women of childbearing potential not using medically accepted forms of contraception. * Current use of the excluded psychiatric medications. * Known hypersensitivity to oxytocin * Known hyponatremia.