Ablation as First Line Treatment in Paroxysmal Atrial Fibrillation

Inclusion Criteria: * Age between 18 and 65 * At least three episodes of paroxysmal atrial fibrillation documented on an electrocardiogram or event recording during the last three years * Never taken antiarrhythmic drugs or at most a pill in the pocket approach * Willingness, ability and commitment to participate in baseline and follow-up evaluations Exclusion Criteria: * Paroxysmal AF for more than three years * An episode of atrial fibrillation that lasted more than seven days within the past six months * Persistent/permanent atrial fibrillation * Atrial fibrillation from reversible cause (i.e. surgery, hyperthyroidism, pericarditis) * Documented atrial flutter * Structural heart disease of clinical significance including: * Cardiac surgery within six months of screening * Unstable symptoms of congestive heart failure (CHF) including NYHA Class III or IV CHF at screening and/or ejection fraction \<30% as measured by echocardiography or catheterization * Unstable angina * Myocardial infarction within six months of screening * Surgically corrected atrial septal defect with a patch or closure device * LA size \> 40mm * Any prior ablation of the pulmonary veins * Enrollment in any other ongoing protocol * Untreatable allergy to contrast media * Pregnancy * Any contraindication to cardiac catheterization * Prosthetic mitral heart valve * Poor general health that, in the opinion of the Investigator, will not allow the patient to be a good study candidate (i.e. other disease processes, mental capacity, etc.) * Contraindication to coumadin or heparin * History of pulmonary embolus or stroke within one year of screening * Acute pulmonary edema * Atrial clot on TEE regardless of the patient's anticoagulation medication status