Hot flashes occur in as many as two thirds of U.S. women during menopause and are severe enough to require treatment in 20%. Although postmenopausal hormone therapy is effective in suppressing hot flashes, it is associated with increased risk for a variety of serious adverse effects. There is an urgent need for alternative treatments that are effective, safe, and easy to use. In this study, the investigators will compare two different types of behavioral relaxation therapies, paced respiration and music therapy, for treatment of menopausal hot flashes. Effects on frequency of hot flashes, other symptom and quality-of-life outcomes associated with hot flashes, and physiologic measures of sympathetic/parasympathetic activity will be examined.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
123
Practice paced respiration 15 minutes per day for a total of 12 weeks.
Practice music therapy for 15 minutes per day for a total of 12 weeks.
University of California, San Francisco
San Francisco, California, United States
Change in average daily frequency of hot flashes.
Time frame: 4-Weeks and 12-Weeks
Change in subjective severity of hot flashes.
Time frame: 4-weeks and 12-weeks
Change in sympathetic and parasympathetic autonomic nervous system tone.
Time frame: 12 weeks
Change in quality-of-of life measures associated with hot flashes.
Time frame: Weeks 4 and Weeks 12
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