Randomized Double Blinding Controlled Study on" Jia Wei Xiao Yao Jiaonang" Treating Mild to Moderate Major Depressive Disorder

Inclusion Criteria: * Patients 18 years or older. * A diagnosis of MDD, single episode or recurrent, according to DSM-IV * Meets DSM-IV criteria for Major Depressive Disorder. * factor score from the 24-item Hamilton Depression Rating Scale (HAM-D) \>20,\<35 * Patients must be able to provide written informed consent Exclusion Criteria: * Patients with a current (or within 6 months prior to the Screening Visit) Axis I disorder of Post Traumatic Stress Disorder, Eating Disorder, Obsessive Compulsive Disorder. * Patients with a history of schizophrenia, schizoaffective disorder or bipolar I or II disorder (with a history of hypomanic or manic episodes). * Patients who meet DSM-IV criteria for substance abuse (alcohol or drugs) within 3 months prior to Screening Visit or substance dependence within 6 months prior to the Screening Visit. * Patients who meet criteria for any of the following DSM-IV MDD Specifiers: \[a\] With Catatonic Features; \[b\] With Postpartum Onset; \[c\] With Seasonal Pattern \[d\] with Psychotic Features. * Patients who are receiving formal psychotherapy or have had psychotherapy within the 12 weeks prior to the Screening Visit.