Study of LV5FU2 Versus FOLFOX for Curatively-resected, Node-positive Esophageal Squamous Cell Carcinoma

Inclusion Criteria: * Aged 20 years or older * Histologically confirmed squamous cell carcinoma of esophagus * Curatively (R0) resected, lymph node positive * ECOG performance status of 0 or 1 * Restoration of oral intake \>1500 kcal/d * No prior chemotherapy except for neoadjuvant ones * No prior radiotherapy within 1 month before registration * Adequate marrow, hepatic, renal and cardiac functions * Provision of a signed written informed consent Exclusion Criteria: * Severe co-morbid illness and/or active infections * Prior treatment with oxaliplatin * Pregnant or lactating women * Active CNS metastases not controllable with radiotherapy or corticosteroids * Known history of hypersensitivity to study drugs