Platelet Inhibition and Bleeding in Patients Undergoing Emergent Cardiac Surgery

Medical University of Graz167 enrolled

Overview

The aim of the study is to evaluate if there is an association between platelet inhibition and surgery-related bleeding in patients undergoing emergent cardiac surgery during dual antiplatelet therapy.

Blood for measuring platelet function is drawn before induction of anesthesia

Study Type

OBSERVATIONAL

Enrollment

167

Conditions

Bleeding

Eligibility

Sex: ALLMin age: 30 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * First time on-pump CABG with or without valve replacement Exclusion Criteria: * Redo surgery, * Renal insufficiency needing dialysis, * Concomitant medication with warfarin, * Preoperative fibrinogen \< 150 mg%

Locations (1)

Department of Anesthesiology and Intensive Care Medicine, Department of Surgery, Medical University of Graz

Graz, Austria

Outcomes

Primary Outcomes

Calculated Blood Loss

Time frame: until postoperative day 5

Secondary Outcomes

BARC Bleeding

Intracranial bleed within 48 hours, Reoperation after closure of sternotomy for the purpose of controlling bleeding, Transfusion of equal to or more than 5 Units of packed red blood cells within a 48-hour period, Chest tube output of equal to or more than 2 L within a 24-h period.

Time frame: until postoperative day 2

Data from ClinicalTrials.gov

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