The purpose of this study is to measure systemic levels of vascular endothelial growth factor (VEGF) and other proteins (e.g. IGF-1) in the systemic circulation of infants with retinopathy of prematurity (ROP) following ocular treatment with either intravitreal injections of anti-VEGF agents or retinal laser photocoagulation. The primary aim is to determine if serum VEGF levels change after treatment.
Study Type
OBSERVATIONAL
University Eye Hospital
Freiburg im Breisgau, Baden-Wurttemberg, Germany
Systemic VEGF levels following treatment
comparing VEGF levels in serum of ROP infants treated with intravitreal anti-VEGF agents vs. retinal laser photocoagulation over 16 weeks post treatment
Time frame: 16 weeks
Systemic levels of other growth factors (e.g. IGF-1)
comparing systemic levels of other (non-VEGF) factors in serum of ROP infants treated with intravitreal anti-VEGF agents vs. retinal laser photocoagulation
Time frame: 16 weeks
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