The purpose of this study is to determine the effect of various foods and/or food substances such as fats or proteins on the blood glucose and insulin concentrations in people with and without type 2 diabetes.
Various foods or food substances are given as a test meal. The metabolic response is determined at various times after the administration of the meal (e.g. blood glucose, and other hormones and metabolites).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
300
240 ml water, 50 g glucose ± 1 mmol amino acid/kg lean body mass
Minneapolis VA Health Care System
Minneapolis, Minnesota, United States
Change in blood glucose concentration
Test substances will be given at 0800 hr and blood drawn at several time points up to 5 hours after the meal.
Time frame: several time points after ingestion of test substance
Change in serum insulin concentration
Test substances will be given at 0800 hr and blood drawn at several time points up to 5 hours after the meal.
Time frame: Several time points after ingestion of test substance
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