Is goal directed fluid therapy reducing postoperative complications in comparison to traditional fluid therapy for gastro surgical ASA III/IV patients? The investigators compare two groups of patients: one group receives goal directed fluid therapy guided by LiDCOrapid stroke volume variation (SVV), the other gets the "traditional" fluids, ie the current regime.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
30
Standard monitoring. The patient is connected to the LiDCOrapid monitor via an arterial line placed in a.radialis. A bolus of 500 ml Ringer acetate is given before anesthesia. If the stroke volume (SV) increases more than 10%, repeat the procedure until the SV is not increasing. After that, induction of anesthesia. Maintenance fluid is given as Ringer acetate 2ml/kg/t. Continuous monitoring of stroke volume variation (SVV). If SVV\> 10%, give a fluid bolus 6ml/kg Ringer acetate. Repeat until SVV \<10%. Bleeding is being replaced 1:1 with hydroxyethyl starch. SAG by bleeding \>1000ml. By fall in blood pressure and SVV \<10%, start vasoactive treatment with epinephrine. Postoperative is given Glucose 5% 80ml/h.
Oulu University Hospital, Department of Anesthesia and Intensive Care
Oulu, Finland
Haukeland University Hospital
Bergen, Norway
Stavanger Universityhospital, Division for medical service, anesthesia and intensive care
Stavanger, Norway
Postoperative complications
Time frame: 5 days after surgery
Length of hospital stay
Time frame: 3 month after surgery
Complications until discharge and readmission within 30 days
Time frame: 3 month after surgery
Mortality within 30 days and 3-month after surgery
Time frame: 3 month after surgery
Renal function
defined by RIFLE criteria
Time frame: 5 days after surgery
Vasoactive agents need
Difference in the number of patients in need of vasoactive agents, during surgery and in the postoperative period.
Time frame: 3 month after surgery
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