Probiotic Sport Study

Green Beat24 enrolled

Overview

We investigate the impact of a probiotic-based dietary supplement on oxidative stress and endotoxemia before and after strenuous exercise. Hypotheses (H1): * Supplementation has an influence on oxidative stress parameters before and post exercise * Supplementation has an influence on parameters of endotoxemia and inflammation before and post exercise * Strenuous exercise has an influence on parameters of oxidative stress, inflammation and endotoxemia

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

Conditions

Oxidative Stress Inflammation Endotoxemia

Interventions

probiotic-based dietary supplementDIETARY_SUPPLEMENT

24 trained men receive a probiotic-based dietary supplement for 16 weeks. Dosage 3x 10-9 per day

placeboDIETARY_SUPPLEMENT

24 trained men receive a placebo for 16 weeks with same dosage compared to active group

Eligibility

Sex: MALEMin age: 30 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * trained men * 30 - 45 years * non-smokers * 4wk wash out of all dietary supplements Exclusion Criteria: * untrained people (VO2max \< 55 ml x kg-1) * female * all people not matching this age group * smokers * all men taking dietary supplements * all men that fail in ergometric exercise eligibility testing, refering to the standards in sports medicine (e.g.: significant ST-decrease or increase, blood pressure \> 240 mmHg, tachycardia, polymorphic extrasystolia, cyanosis, bradyarrhythmia..) * all people that are not adjudged as "Healthy"

Locations (1)

Medical University of Graz

Graz, Austria

Outcomes

Primary Outcomes

markers of oxidative stress, endotoxemia and inflammation

Time frame: 6 months

Data from ClinicalTrials.gov

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