Migraine is the most common recurrent headache. Current therapy of migraine headache consists of multiple drug groups for control of attack and prophylaxis against recurrent attacks. Emerging alternative medicine worldwide led investigators to evaluate the efficacy of cupping therapy plus SERKANGABIN syrup in treatment of migraine headache. Severity, duration and frequency of attacks of migraine headache evaluated in two groups during six months from presentation.
In a randomized controlled trial investigators randomly assigned 76 patients with migraine to cupping therapy plus SERKANGABIN or to receive conventional medical treatment. The use of CAM in migraine is a growing phenomenon. Migraine patients seek and explore both conventional and CAM approaches. Wet cupping is an ancient medical technique still used in several contemporary societies. It is being used in management of hypertension, diabetes mellitus, and headaches, renal and biliary stones and for maintaining health. Little experimental study has been devoted to test its efficacy to treat migraine headache. Investigators planned this study for evaluation of therapeutic efficacy of wet cupping and an Iranian traditional medicine preparation, SERKANGABIN in treatment of migraine headache compared with current medicine protocols. SERKANGABIN is a preparation of honey, vinegar and distilled mint water that in traditional Iranian medicine is believed to have therapeutic effects in many diseases (diabetes mellitus, hypertension, hyperlipidemia, osteoarthritis, chronic obstructive airway disease, interstitial lung disease, hepatitis, fatty liver, ischemic heart disease, migraine, cerebrovascular diseases)
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
391
wet cupping serkangabin syrup
nortriptyline ,propranolol ,ergotamine , sumatriptan tablets
Birjand University of Medical Sciences,Valiasr Hospital
Birjand, South Khorasan Province, Iran
frequency of migraine attacks per week
endpoints evaluated in both study groups 2 weeks after first presentation and receiving treatment protocols
Time frame: 2 weeks after first presentation
severity of migraine attacks
severity of migraine attacks evaluated 2 weeks after first presentation in two study groups
Time frame: 2 weeks after first presentation
duration of migraine attacks
duration of migraine attacks evaluated 2 weeks after first presentationin two study groups
Time frame: 2 weeks after first presentation
severity of migraine attacks
severity of migraine attacks evaluated 1 month after first presentation in two study groups
Time frame: 1 month after first presentation
severity of migraine attacks
severity of migraine attacks evaluated 3 months after first presentation in two study groups
Time frame: 3 months after first presentation
severity of migraine attacks
severity of migraine attacks evaluated 6 months after first presentation in two study groups
Time frame: 6 months after first presentation
duration of migraine attacks
duration of migraine attacks evaluated 1 month after first presentation in two study groups
Time frame: 1 month after first presentation
duration of migraine attacks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
duration of migraine attacks evaluated 3 months after first presentation in two study groups
Time frame: 3 months after first presentation
duration of migraine attacks
duration of migraine attacks evaluated 6 months after first presentation in two study groups
Time frame: 6 months after first presentation
frequency of migraine attacks
frequency of migraine attacks evaluated 1 month after first presentation in two study groups
Time frame: 1 month after first presentation
frequency of migraine attacks
frequency of migraine attacks evaluated 3 months after first presentation in two study groups
Time frame: 3 months after first presentation
frequency of migraine attacks
frequency of migraine attacks evaluated 6 months after first presentation in two study groups
Time frame: 6 months after first presentation